neuroprotective effects — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2009	SB-3CT		MMP
	SB-3CT is a potent and specific gelatinase inhibitor for MMP-2(Ki=13.9 nM) and MMP-9(Ki=600 nM).		MMP
T8516	Levomenol	(-)-α-BISABOLOL	Others
	Levomenol ((-)-α-BISABOLOL) is a sesquiterpene alcohol that has been found in the essential oils of several aromatic plants, with exerts antioxidant, anti-inflammatory, and anti-apoptotic activities.		Others
T3026	(-)-Huperzine A	HupA,Huperzine A	Apoptosis , AChR , AChE , iGluR
	(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the tr...		Apoptosis , AChR , AChE , iGluR
T6606	Nicaraven		Others
	Nicaraven, a hydroxyl radical scavenger, has neuroprotective and antivasospastic effects.		Others
T14526	Bemesetron	TROPANYL 3,5-DICHLOROBENZOATE,3-TROPANYL-3,5-DICHLOROBENZOATE,MDL 72222	5-HT Receptor
	Bemesetron (MDL 72222) is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective effects.		5-HT Receptor
T6201	Disufenton sodium	Cerovive,NXY059,OKN007,NXY-059,NXY 059	Reactive Oxygen Species
	Disufenton sodium (NXY-059), a new-type nitrone, exhibits potently neuroprotective effects.		Reactive Oxygen Species
T28118	MSP3	MSP-3,MSP 3	TRP/TRPV Channel
	MSP3 is an agonist of TRPV1 (EC50 = 0.87 μM) and shows antinociceptive and neuroprotective effects.		TRP/TRPV Channel
TN1076	Oleonuezhenide		Others
	Oleonuezhenide is a natural product from Chinese formula Ligustrum lucidum, exerts neuroprotective effects and also considered as treatment of osteoporosis.		Others
TP1856	Colivelin		Beta Amyloid , STAT
	Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).		Beta Amyloid , STAT
T6699	Tempol	TMPN,Tanol,4-Hydroxy-TEMPO	Reactive Oxygen Species , ROS , Autophagy
	Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.		Reactive Oxygen Species , ROS , Autophagy
TMS1743	Salvigenin		MAO , Autophagy , ROS Kinase
	Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.		MAO , Autophagy , ROS Kinase
T22810	GR 89696 fumarate		Opioid Receptor
	GR 89696 fumarate is a highly selective κ2 opioid receptor agonist (IC50 = 0.04nM) with anti-pruritchy, anti-injury and neuroprotective effects.		Opioid Receptor
T0136	Citicoline	CDP-Choline,Citicholine,cytidine 5'-diphosphocholine,cytidine diphosphate-choline	Apoptosis , Dopamine Receptor , Endogenous Metabolite
	Citicoline (CDP-Choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.		Apoptosis , Dopamine Receptor , Endogenous Metabolite
T1864	Fabomotizole	Obenoxazine,CM346	Others
	Fabomotizole (Obenoxazine) is an anxiolytic drug; produces anxiolytic and neuroprotective effects without any sedative or muscle relaxant actions.		Others
T3714	SUN11602	SUN 11602	ERK , FGFR
	SUN11602, an aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. It mimics the neuroprotective effects of bFGF and prevents glutamate-induced neuronal death. It also increases level...		ERK , FGFR
T5721	Dehydroevodiamine hydrochloride		AChE
	Dehydroevodiamine (DHE), a natural compound isolated from Evodia rutaecarpa, can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitric oxide production.		AChE
T26288	Clovamide	trans-Clovamide,N-trans-Caffeoy-L-dopa	Apoptosis , Influenza Virus , ROS , Antibacterial
	Trans-Clovamide (trans-Clovamide) is a naturally occurring caffeoyl conjugate identified in the antioxidant polyphenolic fraction of cocoa (T. cacao L.) Trans-Clovamide is a potent antioxidantand that has shown neuroprot...		Apoptosis , Influenza Virus , ROS , Antibacterial
T2780	Catalpol	Catalpinoside,Digitalis purpurea L	Others , HBV
	Catalpol (Catalpinoside) is an iridoid glycoside with neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.		Others , HBV
T39341	FCPR03		PDE
	FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively. FCPR03 has neuroprotective, anti-inflammatory, and antidepr...		PDE
T8030	Ethyl pyruvate		Apoptosis , Antioxidant
	Ethyl pyruvate is a simple aliphatic ester of pyruvic acid and has been shown to have robust neuroprotective effects via its anti-inflammatory, anti-oxidative, and anti-apoptotic functions.		Apoptosis , Antioxidant